NT & first screening results...

NT & first screening results...

liz Portland OR
liz Portland OR

August 18th, 2012, 2:29 am #1

Hello ladies
would like your opinion on my tests today, I am 42 (yikes) & 12 wks.
NT = 1.4
CRL = 59.6
they don't measure the nasal bone...
so combined w/ my bloodwork my risk for Downs is 1 in 801 (w just my age it's 1 in 41)
my risk for T 18 & 13 is 1 in 1107 ( just based on my she it's 1 in 73).
I paid out of pocket to do the MaterniT21 test today - $475.00.
Still very neurotic about everything about my age & may still do an Amnio just to be certain.
Not sure...
Thoughts ?

Thanks in advance,
Liz

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BroodyHen
BroodyHen

August 18th, 2012, 5:23 am #2

my odds, with a good nuchal measurement, got worse with the blood work in the first trimester test (1:32, down from my age risk of 1:48 and i'm 43.5). i got a negative on the materniT21 test, but it was somewhat ambiguous. for me, i just decided i need to know - i am scheduled for an amnio in a couple of weeks. i am terrified about the MC risk, but i don't want to spend my pregnancy wondering and worried. this will be my #2, so maybe that is influencing my decision, i don't know. it is just really, really tough to decide what to do. but your odds are really good, especially for your age. when your odds improve after the screening test, i think that is a really good thing. you could also wait for the anatomy scan and try to get it at 18 weeks and see if US detects any problems. that combined with your favorable odds and the materniT21 might just be enough to put you at ease.

i feel for you - it is crazy making trying to decide what to do. if you haven't already, you might talk with a genetic counselor. mine actually didn't help all that much, but i think that was really because there aren't any certainties in all this. but i think you should take comfort in your numbers. good luck with this. i still struggle - i think i spend a little bit of each day contemplating talking myself out of the amnio! neurotic, indeed
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Teresa
Teresa

August 18th, 2012, 11:41 am #3

Hello ladies
would like your opinion on my tests today, I am 42 (yikes) & 12 wks.
NT = 1.4
CRL = 59.6
they don't measure the nasal bone...
so combined w/ my bloodwork my risk for Downs is 1 in 801 (w just my age it's 1 in 41)
my risk for T 18 & 13 is 1 in 1107 ( just based on my she it's 1 in 73).
I paid out of pocket to do the MaterniT21 test today - $475.00.
Still very neurotic about everything about my age & may still do an Amnio just to be certain.
Not sure...
Thoughts ?

Thanks in advance,
Liz
Hi, Liz

I think your numbers are actually REALLY good for your age. I'm not so sure you even tested "high risk" - I think it's anything under 1 in 270. If you go back a few pages, you can read what happened to me, I (was 39.11 years old when blood was taken) tested 1 in 127 for Down Syndrome. Since DH and I didnt want to do Amnio or CVS (4 losses under my belt and the risk of m/c for these procedures were way too high for us) we opted for the MaterniT21 test and like you, paid the $475.

Our results came back negative but as you know, it's 99.1% accurate for DS. Still, we felt VERY good about this.

I will also tell you that I was very hesitant to do the second part of the blood work (AFP test, etc) We were warned that because we had high risk results for the NT scan/blood, that we should prepare for the second part to also come back high. However, my results for the AFP and other bloodwork were amazing. I don't have the exact numbers but they were that of a 20 year old. Go figure!

IMO, why don't you wait to see how your MaterniT21 test results come back before making any decisions about doing the amnio. Because I would do that only if they come back positive. Just my opinion, I know there are others here who have had it done and were relieved to have a definitive answer. If you do decide, make sure you go to a clinic with amazing stats.


Good luck, that wait for the MT21 results is GRUELING...but we're so lucky to have had that option.







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Sara H
Sara H

August 18th, 2012, 2:30 pm #4

Hello ladies
would like your opinion on my tests today, I am 42 (yikes) & 12 wks.
NT = 1.4
CRL = 59.6
they don't measure the nasal bone...
so combined w/ my bloodwork my risk for Downs is 1 in 801 (w just my age it's 1 in 41)
my risk for T 18 & 13 is 1 in 1107 ( just based on my she it's 1 in 73).
I paid out of pocket to do the MaterniT21 test today - $475.00.
Still very neurotic about everything about my age & may still do an Amnio just to be certain.
Not sure...
Thoughts ?

Thanks in advance,
Liz
Number are numbers, they can frustrate us or helps us.

(I think your number thus far look great!

I know I look at them so differently now...

Less than a 1 percent chance I could ever get PG, I was told. Beat that!

Chance I'd find this board online and get the help I needed from brilliant ladies? 1-10,000! Beat that!

Chance that, with all my odd issues piling up we'd get this far? Very slim. Beat that!

So, when other friends felt that a 1 in 150 chance of miscarriage was worth it, it was NOT to me because I have beaten MUCH worst odds before! It's all relative to your experience, you know?

I would say this, thought as another way of looking at it:

let's be Math-y about it...
$500 seems like a lot but lets do some more math! (Yeah!) If you are 12 weeks now you have, hopefully, 28 more weeks. 28 weeks, times 7 days a week, is 196. So you have 196 days in this pregnancy. $500 divided by 196 is $2.55 a day. For you is it worth $2.55 a day to not be stressed?

On the other hand, as you have seen from posts, there can be false readings, an inability to read correctly and other stuff so keep that in mind, too!

At the end of the day it really come down to this: What will you do with the info? (No need to answer that to us, just to you!) Would it change your plans or help you get ready if there was something to be aware of? Would you take measures or do you just want to know so you are forwarded? If you are NOT going to change your plans then you might, if you feel at ease enough, wait. At over 35 we are all "high risk" so there will be other scans and, probably (there are those pesky numbers again!) they would see other markers. (Though, I know, sometimes they don't, just so you are aware.)

As I often say, the best way for me to make a choice is to make one, see how I feel and my heart feels, then change my mind and see how that feels, too. Usually at the end I know what to do!

So, follow your heart!

Good luck to you and be well!
Sara H
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Joined: January 26th, 2011, 6:36 pm

August 18th, 2012, 3:01 pm #5

Hello ladies
would like your opinion on my tests today, I am 42 (yikes) & 12 wks.
NT = 1.4
CRL = 59.6
they don't measure the nasal bone...
so combined w/ my bloodwork my risk for Downs is 1 in 801 (w just my age it's 1 in 41)
my risk for T 18 & 13 is 1 in 1107 ( just based on my she it's 1 in 73).
I paid out of pocket to do the MaterniT21 test today - $475.00.
Still very neurotic about everything about my age & may still do an Amnio just to be certain.
Not sure...
Thoughts ?

Thanks in advance,
Liz
look good to me, but as others have said, they are just numbers and they are enough to make us crazy!

I would wait to see what the Materniti21 results come back with and then make your decision. I had an amnio with my first b/c my numbers were not good and I needed definitive results that all was okay, so I didn't spend my whole pregnancy worried and filled with anxiety. Of course the risk of m/c with the amnio frightened me, but the specialist at my clinic had way better rates than the average. These decisions are so difficult and I wish you the best in whatever you decide.

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jkl
jkl

August 19th, 2012, 6:02 pm #6

Hello ladies
would like your opinion on my tests today, I am 42 (yikes) & 12 wks.
NT = 1.4
CRL = 59.6
they don't measure the nasal bone...
so combined w/ my bloodwork my risk for Downs is 1 in 801 (w just my age it's 1 in 41)
my risk for T 18 & 13 is 1 in 1107 ( just based on my she it's 1 in 73).
I paid out of pocket to do the MaterniT21 test today - $475.00.
Still very neurotic about everything about my age & may still do an Amnio just to be certain.
Not sure...
Thoughts ?

Thanks in advance,
Liz
your risks for m/c from the amnio are much higher than your risks for having baby with any of those trisomies. Those are pretty good odds for 42, I am the same age and my numbers were 1:209, which was still not considered a positive screen, so we didn't do further testing. I would think combined with the materni21 test you should be pretty reassured.

jkl
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Joined: November 18th, 2009, 5:41 pm

August 19th, 2012, 11:20 pm #7

Hello ladies
would like your opinion on my tests today, I am 42 (yikes) & 12 wks.
NT = 1.4
CRL = 59.6
they don't measure the nasal bone...
so combined w/ my bloodwork my risk for Downs is 1 in 801 (w just my age it's 1 in 41)
my risk for T 18 & 13 is 1 in 1107 ( just based on my she it's 1 in 73).
I paid out of pocket to do the MaterniT21 test today - $475.00.
Still very neurotic about everything about my age & may still do an Amnio just to be certain.
Not sure...
Thoughts ?

Thanks in advance,
Liz
I would get the amnio. I did CVS with my first pregnancy because we were given 1 in 3 odds of chromosomal issues. We weren't sure what we would do if it came back positive but we wanted the information so we could talk to experts, etc. We knew a couple who had gotten low odds and not done CVS/amnio and then gave birth to a baby with Down Syndrome. They were completely taken off guard and the baby had a major heart defect on top of everything. We did not want to be surprised. So we found the best perinatologist in Seattle and went for it. I trusted him completely and there were no problems -- test came back negative and all was fine. With my second pregnancy, the numbers we were given based on the first trimester screening were good, so we waited and did an amnio with the same doctor that we went to for the CVS. Again it was no big deal and the results were fine. I also had to do an amnio with each baby at 38 weeks to check lung function before delivery (long story). Both amnios were fine. I am a big proponent of amnios, but I'm sure if I knew someone who had problems because of an amnio, I would probably feel more cautious about them.

good luck to you!
Sarah
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