FSH fluctuations?

FSH fluctuations?

double L
double L

September 10th, 2006, 7:00 pm #1

I'm 43, but with very little experience ttc. I'm single and have done 2 donor IUI's. Last September, my day 3 FSH was 6.1. This July it was 13.7, and I assumed this significant increase was due to my age. Last month, we skipped the CD3 reading, but on day 9 (2 days before ovulation) my FSH was 7.1.

Today is CD3, and my baseline readings are: Estradiol 74; FSH 5.4; LH 4.1; Progesterone 1.1. I had one follicle on each side: 1.09 & 1.59 cm, along with several smaller ones.

Can those of you with more experience give me any insight? Do your numbers fluctuate a great deal? Are the months with lower FSH considered more likely for successful ttc? Do my other readings seem unusual?

I have had a consultation with Dr. Check in NJ, and am considering whether to move from IUI to IVF because of age and my July high FSH reading. I will speak with him on Tuesday night. Any thoughts? Any questions you'd recommend I ask?

Thanks!
double L
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Jule
Jule

September 10th, 2006, 10:15 pm #2

I can tell you that FSH does fluctuate every month. Mine has been 6.5, 7.5, 12.9, etc. Its always a different number. The months where FSH is lower are considered to be more ideal for conception.

My own opinion is that IVF would be better for you than IUI. IVF has much better success rates overall than IUI.
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Joined: August 2nd, 2004, 9:44 am

September 11th, 2006, 3:56 am #3

I'm 43, but with very little experience ttc. I'm single and have done 2 donor IUI's. Last September, my day 3 FSH was 6.1. This July it was 13.7, and I assumed this significant increase was due to my age. Last month, we skipped the CD3 reading, but on day 9 (2 days before ovulation) my FSH was 7.1.

Today is CD3, and my baseline readings are: Estradiol 74; FSH 5.4; LH 4.1; Progesterone 1.1. I had one follicle on each side: 1.09 & 1.59 cm, along with several smaller ones.

Can those of you with more experience give me any insight? Do your numbers fluctuate a great deal? Are the months with lower FSH considered more likely for successful ttc? Do my other readings seem unusual?

I have had a consultation with Dr. Check in NJ, and am considering whether to move from IUI to IVF because of age and my July high FSH reading. I will speak with him on Tuesday night. Any thoughts? Any questions you'd recommend I ask?

Thanks!
double L
My FSH has fluctuated between 8.5 and 18.8 over the past 18 months (see sig lines below) and I have noticed NO difference whatsoever in my response to stims, likelihood of conceiving (I've had 4 chem pgs in that time), or anything else. So, it fluctuates a lot and IMHO it doesn't mean much.

Your baseline follies sound quite large for day 3, which is probably the reason your E2 is a little high (which means your follicles have already started developing). When E2 is high it makes FSH read low, so that's why you are down at 5.4. The other readings look fine to me, although I don't know much about pre-O progesterone levels.

If you're 43 I would definitely jump to IVF as soon as you can. You can always go back to IUI, but delaying trying IVF until you are older (and likely to respond more poorly) would not be a good idea. So, if you are ever going to do it, do it now, that's my vote.

Good luck,
Kiwichick

<a href="http://www.fertilityfriend.com/home/kiwichick">
<img border="0" src="http://www.fertilityfriend.com/ticker/k ... c.png"></a>

Me 41, DH 44
Highest FSH 19.6 (8/2003); latest FSHs 9.6 (4/05), 9.7 (6/05), 12.4 (10/05), 8.5 (1/06), 18.8 (2/06), 16.4 (4/06), 9.0 (7/06)
DD 2 yrs (IUI/Clomid high FSH baby)
ttc#2 since March 2005, two failed IUIs (Clomid)
Doing acupuncture (since 6/05, Chinese herbs and supplements, DHEA (since 12/05), occasional wheatgrass; added baby aspirin and 5mg folic acid from 4/06. DH doing acu, herbs, Vitamin C (under duress).
IVF#1 (MDL) cancelled (July 2005)
Chemical pg on a break cycle (Aug 2005)
IVF#2 - 2 embies, BFN (Nov 2005)
Chemical pg on a break cycle (Jan 2006)
Chemical pg on a break cycle (March 2006)
IVF#3 - 4 embies, 3 t/f, chemical pg (May 2006)
IVF#4 - 3 embies, BFN (Aug 2006)
IVF#5 - Nov 2006
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Hopeful_Sandy
Hopeful_Sandy

September 11th, 2006, 4:11 am #4

I'm 43, but with very little experience ttc. I'm single and have done 2 donor IUI's. Last September, my day 3 FSH was 6.1. This July it was 13.7, and I assumed this significant increase was due to my age. Last month, we skipped the CD3 reading, but on day 9 (2 days before ovulation) my FSH was 7.1.

Today is CD3, and my baseline readings are: Estradiol 74; FSH 5.4; LH 4.1; Progesterone 1.1. I had one follicle on each side: 1.09 & 1.59 cm, along with several smaller ones.

Can those of you with more experience give me any insight? Do your numbers fluctuate a great deal? Are the months with lower FSH considered more likely for successful ttc? Do my other readings seem unusual?

I have had a consultation with Dr. Check in NJ, and am considering whether to move from IUI to IVF because of age and my July high FSH reading. I will speak with him on Tuesday night. Any thoughts? Any questions you'd recommend I ask?

Thanks!
double L
I just wanted to say that, wow, your FSH numbers are great for 43!! I sure wish mine were that great when I was that age....

Best of luck to you,

Sandy
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double L
double L

September 11th, 2006, 5:22 am #5

My FSH has fluctuated between 8.5 and 18.8 over the past 18 months (see sig lines below) and I have noticed NO difference whatsoever in my response to stims, likelihood of conceiving (I've had 4 chem pgs in that time), or anything else. So, it fluctuates a lot and IMHO it doesn't mean much.

Your baseline follies sound quite large for day 3, which is probably the reason your E2 is a little high (which means your follicles have already started developing). When E2 is high it makes FSH read low, so that's why you are down at 5.4. The other readings look fine to me, although I don't know much about pre-O progesterone levels.

If you're 43 I would definitely jump to IVF as soon as you can. You can always go back to IUI, but delaying trying IVF until you are older (and likely to respond more poorly) would not be a good idea. So, if you are ever going to do it, do it now, that's my vote.

Good luck,
Kiwichick

<a href="http://www.fertilityfriend.com/home/kiwichick">
<img border="0" src="http://www.fertilityfriend.com/ticker/k ... c.png"></a>

Me 41, DH 44
Highest FSH 19.6 (8/2003); latest FSHs 9.6 (4/05), 9.7 (6/05), 12.4 (10/05), 8.5 (1/06), 18.8 (2/06), 16.4 (4/06), 9.0 (7/06)
DD 2 yrs (IUI/Clomid high FSH baby)
ttc#2 since March 2005, two failed IUIs (Clomid)
Doing acupuncture (since 6/05, Chinese herbs and supplements, DHEA (since 12/05), occasional wheatgrass; added baby aspirin and 5mg folic acid from 4/06. DH doing acu, herbs, Vitamin C (under duress).
IVF#1 (MDL) cancelled (July 2005)
Chemical pg on a break cycle (Aug 2005)
IVF#2 - 2 embies, BFN (Nov 2005)
Chemical pg on a break cycle (Jan 2006)
Chemical pg on a break cycle (March 2006)
IVF#3 - 4 embies, 3 t/f, chemical pg (May 2006)
IVF#4 - 3 embies, BFN (Aug 2006)
IVF#5 - Nov 2006
Thanks, Kiwichick!

You mentioned that my E2 level at 74 is slightly high. I remembered that someone had posted this website for info about hormone levels:
http://www.fertilityplus.org/faq/hormonelevels.html

Seems an E2 level of 74 is at the upper edge of "normal" for day 3. So when you say that this makes FSH "read" lower, does this meant that it would otherwise be higher? A couple of you have posted that progesterone support at the end of one cycle may cause early ovulation in the next. Could that make the E2 level higher on day 3?

IUI is pretty simple, but I'm a little scared of IVF and not sure what questions to ask Dr. Check. Someone posted a good IUI explanation site recently. Does anyone know of a similar site for IVF? The closest I've ever come to surgery or a major medical procedure was having my wisdom teeth extracted!


double L
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Joined: August 2nd, 2004, 9:44 am

September 11th, 2006, 7:53 am #6

Yes, sorry, your E2 is at the upper end for normal, although the limit differs from RE to RE. Some like to see it under 50, some say under 75-80. My hunch is that 74 is slightly elevated, but I say that partly because you had two quite big follicles at that stage (they and the E2 are linked). [And yes, it's true that P4 can cause your E2 to be elevated early the next cycle because it delays AF but not the other usual developments, so it's like your true Day 1 is back when you would have got AF and your follies are just developing accordingly.] Anyway, if your E2 had been as low as, say, 40, then yes, probably your FSH would have read a bit higher. But you know what, it really doesn't matter because if the highest you've ever seen it is 13.7, that is a fantastic level for someone your age. Mine was already 19.6 at age 38.5!

I agree IVF is a pretty scary procedure compared to IUI. Two things helped me get to grips with it: (1) All sorts of women have gone through this and survived and (2) It's actually a lot less scary, painful, and risky than childbirth. Someone posted this link on the other board recently, which explains the procedure quite well (animated): http://www.fertilitylifelines.com/advan ... /cycle.jsp

Hope this helps,
Kiwichick
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AllyM
AllyM

September 11th, 2006, 4:03 pm #7

I just wanted to say that, wow, your FSH numbers are great for 43!! I sure wish mine were that great when I was that age....

Best of luck to you,

Sandy
I agree, your FSH numbers are great. Best of luck TTC! I'm a "young" 39 quickly approaching 40, and my high FSH is 26.7. So you are definitely still in the playing field!
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KATY
KATY

May 8th, 2018, 12:57 pm #8

I am 20 and my FSH level is 7.06 .What does it mean ?
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Houston
Houston

May 8th, 2018, 2:07 pm #9

You would probably get more feedback if you post on a new thread.  Was your testing done on Day 3?  If not, then your FSH levels need to be done on day 3.  FSH levels from 0-10 are in the normal range, although I do not know if 7.06 is elevated for a 20 year old.  FSH levels must also be interpreted in combination with your estrogen level because it artificially decreases the FSH level. What was your estrogen level? Also, an AMH test can be helpful and does not have to be done on day 3. Have you had this test done?
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