FSH 19.4, E2 240, day 20, 41 year old, single

FSH 19.4, E2 240, day 20, 41 year old, single

Joined: August 11th, 2012, 5:48 pm

August 11th, 2012, 6:17 pm #1

Hi! Such a great forum. I just found out about my hormone levels yesterday and am not quite sure what to think. I've received my results, but have yet to talk with my doctor about the results. I realize that I should get retested on day 3...am just new to this entire process...

I am a single 41 year old woman who is suddenly facing the reality of possibly not having children because of my age. The man that I am dating has mentioned that he will not ever be interested in having a baby outside of the "natural way" (his words). I have heard other men say the same thing...

I guess my line of questioning is two-fold:
1. Should I be concerned about my hormone levels as listed above?
2. And, has anyone else encountered this point of view from men? The reality is that I would like to be in a committed relationship before getting pregnant...which means I have a few years before that will most likely happen. But, my clock is ticking...it's probably too late to freeze my eggs. Should I be considering alternative methods of getting pregnant now, as single woman? What would you do?

I realize that I have many questions, but any advice/comments/opinions at all about any of the questions would be greatly appreciated! Thank you so much!
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K
K

August 11th, 2012, 6:45 pm #2

What does he mean by natural way? That means he is not interested in alternative reproductive methods such as IVF? I think many of these men don't realize that IVF is very common these days, and even younger couples have to use fertility drugs, IUI or IVF to get pregnant nowadays.
I don't know about egg freezing.

You might consider donor egg as well.
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Joined: August 11th, 2012, 5:48 pm

August 11th, 2012, 8:50 pm #3

I think he means his sperm and her egg...no alternative methods. I've encountered many men with this state of mind, and it's frustrating to me. He is 44 and I am 41...you would think he would know that his/our options are less than perfect at this age? I really don't mean to sound like I'm a man-basher at all..I just wish I understood their fears better. Maybe someone could shed some light?
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K
K

August 11th, 2012, 9:04 pm #4

Are some of his fears financial? Is he worried about the cost of ART? It gets more expensive when you do IVF, especially when donors are involved.
Also has he had his sperm tested? He might need IVF with ICSI if he has fertility problems. The quality of male sperm declines with, that is why most clinics won't accept sperm donors over the age of 40. If he thinks he has no fertility problems, well hopefully not; but he needs to get tested.
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Jen
Jen

August 11th, 2012, 9:20 pm #5

Hi! Such a great forum. I just found out about my hormone levels yesterday and am not quite sure what to think. I've received my results, but have yet to talk with my doctor about the results. I realize that I should get retested on day 3...am just new to this entire process...

I am a single 41 year old woman who is suddenly facing the reality of possibly not having children because of my age. The man that I am dating has mentioned that he will not ever be interested in having a baby outside of the "natural way" (his words). I have heard other men say the same thing...

I guess my line of questioning is two-fold:
1. Should I be concerned about my hormone levels as listed above?
2. And, has anyone else encountered this point of view from men? The reality is that I would like to be in a committed relationship before getting pregnant...which means I have a few years before that will most likely happen. But, my clock is ticking...it's probably too late to freeze my eggs. Should I be considering alternative methods of getting pregnant now, as single woman? What would you do?

I realize that I have many questions, but any advice/comments/opinions at all about any of the questions would be greatly appreciated! Thank you so much!
Hi,

I think it is difficult to determine what is going on since your b/w was done one cd 20. Having an e2 of 240 seems like you may have a mature follicle. Do you know what your p4 is? Also, do you have regular cycles? I started this journey when I missed af. I was 38 then and had a cd 3 fsh of 22. I waited ttc until I was 41.5. I am now 44 and have a lot more issues. Below, is the original response to my very first post. I was under 40 then. You would really need to get your b/w on day 3 and speak to your gyn or RE. I really can't recommend what to do only you know how important this is to you. I have to say I now warn all of my younger friends to think seriously about waiting. It is much harder to get PG as you get older. If you do have high FSH be sure to find an RE that is fsh friendly. I heard just doom and gloom when I started. There are Re's willing to work with us.

I would say though, given that you are 41 when fertility is in decline anyway, you are probably smart to be concerned...

But, the decision to have children is as you say a major one.

Your options, basically, are --
1. ttc now, (with donor sperm if you don't have a partner), via IUI or IVF. If you don't have insurance coverage, cost of these procedures is maybe $1k per cycle for IUI with about a 10% chance of PG per cycle and $10,000 for IVF with maybe a 30% chance. Lots of REs put the odds much lower for high FSHers, but until you try you just don't know. The medications you'll use (with IVF and probably with IUI) will add to the cost.

2. freeze your eggs -- new technology, recently available, babies have been made from frozen/thawed eggs. How reliable this is is unclear and it too costs about $10,000. And is probably more indicated for really young women, say under 25, than our age group.

3. wait, which decreases the odds of your having a child using your own eggs the older you get, but leaves open other options including DE, embryo adoption, and adoption, available to you until at least your mid 40s and quite possibly well beyond that.

Below is more general info. about FSH. These are hard choices and I don't know what to recommend, but with full information about the pros/cons of each I hope you can make the choice that's right for you.

Best wishes,
Alex

FSH info--

1. Having high FSH predicts you are less likely to respond to the stims used to hyperstimulate the ovaries for conventional IVF (these are injectable hormones, FSH and sometimes LH, examples include Gonal-F, Follistim, Repronex, and Bravelle).

(1.a. Many women with high FSH, including probably many who never even know they have have FSH, get PG naturally. In fact, at least one study suggests that high FSHers without other IF problems get PG about as easily as everyone else. But if you need IF treatment for diagnosed or other reasons, having high FSH can complicate matters).

2. However (this is important), some women with high FSH do respond just fine to stims. That is, FSH is a predictor but it is not a perfect predictor. If you have high FSH you are at increased risk for a cancelled cycle. A number of studies (see below for more info.) find that high FSHers who don't get cancelled do about as well as non-high FSHers do at IVF. This is important because while, obviously, a cancelled cycle is a very, very frustrating result, it actually represents a much less costly/invasive procedure than going through a whole IVF cycle and still getting a BFN. In other words, in some ways cancellation isn't necessarily bad (again see below).

3. Besides varying the amount of stims you use, REs can prescribe protocols that differ in other ways. This is very important because Lupron, a drug used in some (not all) cycles appears to over-suppress some high FSHers (prevent them from responding adequately to stims). These women may do just fine, though, if allowed to try an "Antagonist" protocol, one involving NO Lupron and using a drug called Cetrotide or Antagon to prevent ovulation from occurring prematurely (which is what the Lupron is also for -- but it works in a different way from the antagonists). So getting cancelled on one protocol does NOT mean you shouldn't try another.

4. If you want another "estimate" of how likely/unlikely you are to respond to stims, you can get an antral follicle count done via vaginal ultrasound. This counts the number of follicles that are visible in your ovaries ready to ripen -- you want there to be more than 4 total across both ovaries.

5. Another option for high FSHers is no- or low-dose cycles. These skip (or drastically reduce) hyperstimulating the ovaries and focus on harvesting the one or two eggs that (hopefully) develop naturally each month. The downside is, you are relying on just 1-2 eggs to make IVF (a costly, complicated procedure) work. The upside is, no need to respond to stims, cheaper than conventional IVF, and possibly better in that it doesn't mess up the natural process of ripening the eggs. A clinic particularly well known for this approach is the Cooper center in NJ http://www.ccivf.com). It will work with you long-distance and allow you to travel in just for egg retrieval/embryo transfer if you want.

6. Some REs will recommend that women with high FSH use donor eggs. This can be a good option, particularly for women who feel more strongly about getting PG/having a baby quickly than about having a genetic link with their child. However, it's not very time-sensitive -- it works as well for women in their mid 40s as for everyone else. The same is not true if you are ttc with your own eggs, so it makes sense to ttc with your own eggs first and not allow anyone to rush/push you to DE.

http://www.resolve.org/infertility-over ... fertility/

http://fertilityplus.com/faq/hormonelevels.html
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Joined: June 2nd, 2007, 7:45 am

August 12th, 2012, 5:13 am #6

Hi! Such a great forum. I just found out about my hormone levels yesterday and am not quite sure what to think. I've received my results, but have yet to talk with my doctor about the results. I realize that I should get retested on day 3...am just new to this entire process...

I am a single 41 year old woman who is suddenly facing the reality of possibly not having children because of my age. The man that I am dating has mentioned that he will not ever be interested in having a baby outside of the "natural way" (his words). I have heard other men say the same thing...

I guess my line of questioning is two-fold:
1. Should I be concerned about my hormone levels as listed above?
2. And, has anyone else encountered this point of view from men? The reality is that I would like to be in a committed relationship before getting pregnant...which means I have a few years before that will most likely happen. But, my clock is ticking...it's probably too late to freeze my eggs. Should I be considering alternative methods of getting pregnant now, as single woman? What would you do?

I realize that I have many questions, but any advice/comments/opinions at all about any of the questions would be greatly appreciated! Thank you so much!
And I'm not a doctor but your fsh looks suspiciously high for day 20. Get thee to a fert clinic and an acup clinic ASAP would be my two cents worth. At 41 you have absolutely no time to lose. I can't stress this enough. While there are occasional success stories of natural pgs over 40, they are rare .... Please get moving if you are serious about having a baby any which way... Keep us posted.zz
Last edited by phoebegrace on August 12th, 2012, 9:42 pm, edited 1 time in total.
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Joined: August 6th, 2011, 6:43 am

August 12th, 2012, 6:19 am #7

Hi! Such a great forum. I just found out about my hormone levels yesterday and am not quite sure what to think. I've received my results, but have yet to talk with my doctor about the results. I realize that I should get retested on day 3...am just new to this entire process...

I am a single 41 year old woman who is suddenly facing the reality of possibly not having children because of my age. The man that I am dating has mentioned that he will not ever be interested in having a baby outside of the "natural way" (his words). I have heard other men say the same thing...

I guess my line of questioning is two-fold:
1. Should I be concerned about my hormone levels as listed above?
2. And, has anyone else encountered this point of view from men? The reality is that I would like to be in a committed relationship before getting pregnant...which means I have a few years before that will most likely happen. But, my clock is ticking...it's probably too late to freeze my eggs. Should I be considering alternative methods of getting pregnant now, as single woman? What would you do?

I realize that I have many questions, but any advice/comments/opinions at all about any of the questions would be greatly appreciated! Thank you so much!
Well as others have said, you need a test on day three to look at your hormone levels. An antral follicle test would also be helpful as well as an AMH test. I don't know if you have any physical issues that would get in the way of pregnancy. So, if you are serious about getting pregnant with your own eggs then I think you should get to a good fertility clinic and get tested. Don't go to an OB. You need to see an RE as soon as possible.

Start looking at all of your options. As far as having a baby on your own, it just depends how badly you want a baby. If you really really want a child and can afford to take care of one on your own and believe you can do it then I think you should go for it. A lot depends on your financial situation and your support system. There are several women on the Pregnant or Parenting after DE board that are single women who chose to use DE after 40. They love their children and are happy with their decision. You could post on that board for advice as to what to do.

There are many ways to have a baby so just keep an open mind and consider all the options. You can look at the SART website to find an RE near you and look at their statistics with IVF treatments. You could also ask for a referral from women on the boards or from your OB.

I recently had my son via DE at age 44. This is my second marriage. I had my first baby at 30 and that marriage didn't work after my DD was born. So, you can plan to have a baby with someone in a committed relationship and it still may not work out and you would end up single anyways. I would tell my own DD not to wait for a man to have a baby if she were older and wanted a child but wasn't in a committed relationship. But I would help her with the child

As far as dating men and finding one that is willing to do IVF to have a baby, well many women have enough problems convincing their husbands to have babies naturally or IVF. IVF is very expensive. My clinic charges $14,000 and the drugs were $5,000 for my OE cycle. Depending on what area of the country you are in, those are pretty typical fees for an IVF cycle for a woman over the age of 40. So, you have to really want a baby to spend the money to just try and hope it works. But that doesn't mean it is impossible to find a man that is willing to do all of that. Some men really want to have children and some are not all that interested.

I wish you luck in whatever you decide to do!
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Joined: August 6th, 2011, 6:43 am

August 12th, 2012, 1:30 pm #8

I think he means his sperm and her egg...no alternative methods. I've encountered many men with this state of mind, and it's frustrating to me. He is 44 and I am 41...you would think he would know that his/our options are less than perfect at this age? I really don't mean to sound like I'm a man-basher at all..I just wish I understood their fears better. Maybe someone could shed some light?
My DH did not want to go see an RE when I was almost 43 years old. He thought I was perfectly healthy and we could get pregnant naturally. He actually thought we had plenty of time. He also did not want to spend the money. The initial testing alone was about $1,500 all out of pocket. I think it is just fear and wishful thinking and lack of knowledge. If pregnancy doesn't happen by accident then someone has to be the driving force to make it all happen and jump through the hoops. I think it is usually the woman. I waited for my DH to step up to the plate and get excited to try and have a baby and it never happened. So I had to get the ball rolling and push the ball up the hill by myself.

Do you really want to marry this man or be in a committed relationship with him and have a child with him? I have come to find out that if a woman has a baby she should always have a backup plan that she may be doing it on her own anyways.
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Kim
Kim

August 12th, 2012, 3:13 pm #9

Hi! Such a great forum. I just found out about my hormone levels yesterday and am not quite sure what to think. I've received my results, but have yet to talk with my doctor about the results. I realize that I should get retested on day 3...am just new to this entire process...

I am a single 41 year old woman who is suddenly facing the reality of possibly not having children because of my age. The man that I am dating has mentioned that he will not ever be interested in having a baby outside of the "natural way" (his words). I have heard other men say the same thing...

I guess my line of questioning is two-fold:
1. Should I be concerned about my hormone levels as listed above?
2. And, has anyone else encountered this point of view from men? The reality is that I would like to be in a committed relationship before getting pregnant...which means I have a few years before that will most likely happen. But, my clock is ticking...it's probably too late to freeze my eggs. Should I be considering alternative methods of getting pregnant now, as single woman? What would you do?

I realize that I have many questions, but any advice/comments/opinions at all about any of the questions would be greatly appreciated! Thank you so much!
I think he thinks you can get pregnant naturally. My DH was not on board for IVF years ago due to feeling like it could up the odds of birth defects....pushing limits. We have a nephew that is mentally handicapped so that is the source of his concern...not being able to handle that type of situation.

As others posted above, go to a reproductive endocrinologist in your area to get cycle day 3 testing done for FSH, estrogen, and such. You might want to decide to pursue having a child through donor sperm if you are anxious to try now?

Don't wait is all we know to tell you.
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Holly
Holly

August 13th, 2012, 4:15 pm #10

Hi! Such a great forum. I just found out about my hormone levels yesterday and am not quite sure what to think. I've received my results, but have yet to talk with my doctor about the results. I realize that I should get retested on day 3...am just new to this entire process...

I am a single 41 year old woman who is suddenly facing the reality of possibly not having children because of my age. The man that I am dating has mentioned that he will not ever be interested in having a baby outside of the "natural way" (his words). I have heard other men say the same thing...

I guess my line of questioning is two-fold:
1. Should I be concerned about my hormone levels as listed above?
2. And, has anyone else encountered this point of view from men? The reality is that I would like to be in a committed relationship before getting pregnant...which means I have a few years before that will most likely happen. But, my clock is ticking...it's probably too late to freeze my eggs. Should I be considering alternative methods of getting pregnant now, as single woman? What would you do?

I realize that I have many questions, but any advice/comments/opinions at all about any of the questions would be greatly appreciated! Thank you so much!
Beth:

As everyone has stated above it would be in your best interest to see a "professional" i.e. RE!! Your numbers seem high for that stage in your cycle. Your FSH should start declining as you head into the luteal phase. E2 levels generally peak right before ovulation and then plateau out. Every lab is different though and I'd make sure I was having someone draw and intrepret the numbers that is reputable. You could receive 3 different results from 3 different doctors depending on who's analyzing your blood. Do you know what your Day 20 Progesterone is? If it's above 9 that indicates that you might be ovulating.

Good Luck!

Holly
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