negative hcg

negative hcg

anon for now...update
anon for now...update

January 20th, 2012, 3:08 pm #1

So quite bummed after getting a negative beta yesterday. Our doctor did not really have any answers as to why after we transferred 2 8 cell embryos that were "perfect" from a proven donor would not implant other than "it is always a 50/50 chance". He tried to be reassuring that we still had a great chance due to our 5 frozen embryos...still greater than 80% in getting a live birth is what he tried to tell me. So any advice from here on the next step on our way to the FET which he said we could do after one cycle? Should I have any other testing, immune etc? I think I will try acupuncture this time as well so when would I start that? My lining was at least 10 and I was pregnant naturally last year but miscarried at 7 weeks so I can get pregnant.
I am trying to be positive because I know I still have some good frozen ones and have several friends who have had successful frozen cycles. This is such a great resource and I have learned more here than from my physician, etc.....so thank you!
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Joined: December 2nd, 2005, 3:49 pm

January 20th, 2012, 3:54 pm #2

We transferred one "perfect" embie from a young, proven donor and got a BFN. Did acu before and after, bedrest, etc. I had also been pregnant before (live birth) and had no issues other than egg quality. I conceived my twins from the FET (we transferred 2 that time). No acu, no bedrest! This whole thing is such a mystery, you know? It's hard to not have guarantees, for sure. I can say that I really think that the transfer itself had something to do with it in my case. The first time my RE wasn't in town so someone else did it. She was very awkward (I have a tipped uterus) and I had cramping for 2 days. They hadn't given me anything for it. The second transfer my RE did such a great job. Easy, no cramping, and I did take something just in case (don't remember what) to avoid uterine cramping. Apparently my RE has the highest success rates from transfer onward (there are 8 docs in the clinic) so I think there is something to be said for getting the most experienced person to do your transfer. Hang in there...it will happen.
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smrc
smrc

January 20th, 2012, 4:46 pm #3

So quite bummed after getting a negative beta yesterday. Our doctor did not really have any answers as to why after we transferred 2 8 cell embryos that were "perfect" from a proven donor would not implant other than "it is always a 50/50 chance". He tried to be reassuring that we still had a great chance due to our 5 frozen embryos...still greater than 80% in getting a live birth is what he tried to tell me. So any advice from here on the next step on our way to the FET which he said we could do after one cycle? Should I have any other testing, immune etc? I think I will try acupuncture this time as well so when would I start that? My lining was at least 10 and I was pregnant naturally last year but miscarried at 7 weeks so I can get pregnant.
I am trying to be positive because I know I still have some good frozen ones and have several friends who have had successful frozen cycles. This is such a great resource and I have learned more here than from my physician, etc.....so thank you!
and am in the very same boat. We transferred 2 good looking 8-cell embies (10% fragmentation) before the holidays and ended up with an early chem in Jan. We have 3 frozen - 1 of which I was told looks "good" and the other 2 "fairly good" (C.ornell doesn't grade them??). I have to wait 2 cycles before going ahead with my FET but anxious to proceed.

I'll be rooting for you on your FET.

There seems to be no rhyme or reason to this all - just persistence?

smrc
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Joined: September 13th, 2008, 5:13 pm

January 20th, 2012, 5:46 pm #4

So quite bummed after getting a negative beta yesterday. Our doctor did not really have any answers as to why after we transferred 2 8 cell embryos that were "perfect" from a proven donor would not implant other than "it is always a 50/50 chance". He tried to be reassuring that we still had a great chance due to our 5 frozen embryos...still greater than 80% in getting a live birth is what he tried to tell me. So any advice from here on the next step on our way to the FET which he said we could do after one cycle? Should I have any other testing, immune etc? I think I will try acupuncture this time as well so when would I start that? My lining was at least 10 and I was pregnant naturally last year but miscarried at 7 weeks so I can get pregnant.
I am trying to be positive because I know I still have some good frozen ones and have several friends who have had successful frozen cycles. This is such a great resource and I have learned more here than from my physician, etc.....so thank you!
And I think signs point to that being all it is. BFN's suck. Did you do acupuncture? I think if you poll the moms on the board, it's kind of up in the air as to whether that's a major contributing factor, but since I did it on my successful cycle and didn't do it on my unsuccessful cycle, I'm superstitious about it at a minimum. Anyway, have a cry, eat some chocolate, and rest up for your next try. {{Hugs}} Maggie (in VA)
Last edited by maggie1961 on January 20th, 2012, 7:00 pm, edited 1 time in total.
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Joined: March 25th, 2008, 8:46 pm

January 20th, 2012, 9:03 pm #5

I did do acupuncture for about a yr of my ttc days but not for donor egg/embie.
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Mrs. M
Mrs. M

January 21st, 2012, 12:42 am #6

So quite bummed after getting a negative beta yesterday. Our doctor did not really have any answers as to why after we transferred 2 8 cell embryos that were "perfect" from a proven donor would not implant other than "it is always a 50/50 chance". He tried to be reassuring that we still had a great chance due to our 5 frozen embryos...still greater than 80% in getting a live birth is what he tried to tell me. So any advice from here on the next step on our way to the FET which he said we could do after one cycle? Should I have any other testing, immune etc? I think I will try acupuncture this time as well so when would I start that? My lining was at least 10 and I was pregnant naturally last year but miscarried at 7 weeks so I can get pregnant.
I am trying to be positive because I know I still have some good frozen ones and have several friends who have had successful frozen cycles. This is such a great resource and I have learned more here than from my physician, etc.....so thank you!
BFN's are so cruel. I transferred a perfect 8 cell embryo with no fragmantation and perfect lining and got BFN. Did an FET with a fair graded 8 cell embryo with 25% fragmentation and got a BFP with great initial beta. unfortunately had an early miscarriage at 6 weeks. Sometimes I think it is just being lucky. For as much as they understand about all of this, there is so much they don't understand. I hope that if we persist for for long enough we will eventually land on the right side of the statistics, hopefully sooner rather than later. GL with your FET.
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Joined: August 22nd, 2008, 3:29 pm

January 21st, 2012, 5:22 am #7

So quite bummed after getting a negative beta yesterday. Our doctor did not really have any answers as to why after we transferred 2 8 cell embryos that were "perfect" from a proven donor would not implant other than "it is always a 50/50 chance". He tried to be reassuring that we still had a great chance due to our 5 frozen embryos...still greater than 80% in getting a live birth is what he tried to tell me. So any advice from here on the next step on our way to the FET which he said we could do after one cycle? Should I have any other testing, immune etc? I think I will try acupuncture this time as well so when would I start that? My lining was at least 10 and I was pregnant naturally last year but miscarried at 7 weeks so I can get pregnant.
I am trying to be positive because I know I still have some good frozen ones and have several friends who have had successful frozen cycles. This is such a great resource and I have learned more here than from my physician, etc.....so thank you!
and it can be very unsettling to think what was a perfect cycle failed. How can one have faith and move forward after such a cycle especially when FET's often have a lower success stat.

I was one of those too that had a perfect fresh cycle fail. We transferred two perfect blasts....they were rated 20/20 which is the highest rating that our clinic gives. Our embryologist warned us of the strong possibility of twins occurring as she seldom sees embryos this perfect. My lining too was a 10 triple stripe and I had given birth to OE children.

Moving forward with hope at times was difficult but right after we had our chem m/c and a consult with our Dr. we decided that with 8 frozen blasts we had to move forward. I knew however that we had used our best two on our fresh and I had fears that if those didn't implant then what were my odds.

My Dr. ordered blood work...and found I had tested positive for only one thing...factor V leiden...a blood clotting disorder which I thought was interesting. Even though I had had 5 of our oe children...I had taken a low dose aspirin with our last pgcy after a m/c at 12 wks...I'll never know if that helped to improve our implantation chances since I was over 40 as well.

So we decided to include heparin in our next cycle. Also I upped my acupuncture appt's and also booked an acupuncture appt before our transfer at our out of town clinic. It was with a TCM Dr. who specializes on fertility and he worked with our clinic. (my clinic Dr. does acupuncture after the transfer...he has done this for ages and uses needles to quiet the womb and allow implantation to take hold) Also, I made sure to go to yoga at least 3 times a week, I even had a hot stone massage before leaving for our trip to the clinic...drank lots of water to rid my body of toxins. I meditated and visualized that the FET would be successful. My local TCM Dr. would say to me as she could tell I was grieving our lost cycle...to tell myself that 'this is a new day" and just because our fresh cycle had failed didn't determine the destiny of our FET.

Let's see what else did I do to prepare, I did castor oil treatments every night before our cycle...from the time I started my estrace to increase the lining to my uterus, I drank red raspberry leaf tea and did some femoral massage after the castor oil pack treatment. I made sure my diet was whole foods and healthy and I talked to my Dr. about my supplements...we upped my folic acid intact along with a few other supplements that he thought would be helpful...a good mulit vit, cal/mag with D, high quality fish oil, (I took this even though I was also going to take heparin) oh and I also went to my health food store for my wheat grass...I did this to rid my liver of toxins which I think helps all the hormones to function better. My lining was a 11.

We thawed three blasts, all made the thaw, two were rated really good 18/20 and one was a hail mary..13/20....we ended up getting pg with our son.

Two years later, I did the same routine, this time we used fragmin instead of heparin...it's preloaded and only one shot a day...also I didn't do a lupron shot...just started estrace on day 2 and it was a high enough dose to stop ovulation form occurring...this time my lining was a 12 ts...13 in some parts of my uterus. We thawed 3, all made the thaw...they were all blasts and they were rated at 18/20...the same embryologist who had worked with us before said these looked as good as the day she thawed them so warned us again about multiples...since we had just had a singleton last time we were sure that is at best what we would have...at best...boy was I surprised when we ended up with twin DD's.

So FET's work....tell yourself this is a new day. Do what you can to calm your mind and go forward with a positive mindset, do what you can to be in peak health and then you will have no regrets. It can't hurt to have some blood work if you haven't in the past...as you see from my experience...even though I had had healthy OE children...I still did have one issue that may have created an implantation problem with our perfect blasts...who knows but I'm glad that we tweaked the cycle...it made me feel like we were trying something different.

After our fresh cycle failed I met so many women who had also experienced a neg/or chem after their perfect cycle and then less than perfect embryos from their FET brought them their babies.

I hope this helps you move forward, blessings from Hope

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Seymo
Seymo

January 21st, 2012, 4:21 pm #8

So quite bummed after getting a negative beta yesterday. Our doctor did not really have any answers as to why after we transferred 2 8 cell embryos that were "perfect" from a proven donor would not implant other than "it is always a 50/50 chance". He tried to be reassuring that we still had a great chance due to our 5 frozen embryos...still greater than 80% in getting a live birth is what he tried to tell me. So any advice from here on the next step on our way to the FET which he said we could do after one cycle? Should I have any other testing, immune etc? I think I will try acupuncture this time as well so when would I start that? My lining was at least 10 and I was pregnant naturally last year but miscarried at 7 weeks so I can get pregnant.
I am trying to be positive because I know I still have some good frozen ones and have several friends who have had successful frozen cycles. This is such a great resource and I have learned more here than from my physician, etc.....so thank you!
I know what a disappointment this must be (all too well). I too had a recent loss prior to starting DE and I thought DE would be a piece of cake. I also had a perfect 8cell that did not work out. I am glad you have some FE's for the future. I know its only a small consolation but I guess we have to find hope where we can.

PS - I have done it all - acupuncture, herbs, diet, exercise, no exercise, fertility yoga for various cycles, no gluten no white foods, no sugar, low sugar etc - and I find just coordinating all of that causes even more stress and disappointment when it does not work out. I just try to live a decent healthy life, avoid caffeine, 8 hours of sleep, a little yoga and don't pressure myself to do "it all." I feel a lot better now.
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anon for now..thank you all
anon for now..thank you all

January 21st, 2012, 4:46 pm #9

So quite bummed after getting a negative beta yesterday. Our doctor did not really have any answers as to why after we transferred 2 8 cell embryos that were "perfect" from a proven donor would not implant other than "it is always a 50/50 chance". He tried to be reassuring that we still had a great chance due to our 5 frozen embryos...still greater than 80% in getting a live birth is what he tried to tell me. So any advice from here on the next step on our way to the FET which he said we could do after one cycle? Should I have any other testing, immune etc? I think I will try acupuncture this time as well so when would I start that? My lining was at least 10 and I was pregnant naturally last year but miscarried at 7 weeks so I can get pregnant.
I am trying to be positive because I know I still have some good frozen ones and have several friends who have had successful frozen cycles. This is such a great resource and I have learned more here than from my physician, etc.....so thank you!
Thanks everyone....I just keep telling myself we still have a very good chance almost as good as before (at least that is what our doctor has told me). I think I will add acupuncture so at least I feel like I changed something. It is just hard because because it feels like you are led to believe that DE is the golden ticket so perhaps I was a little too confident and felt like we did all the right things (ie proven donor, good lining, etc). I also try to reassure myself with the fact that the first time our donor was used it was also the FET that was the successful cycle. I hate the waiting for the FET....I think he told me 4-6 weeks but to be honest I was in a disappointed daze at that time.
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Pip
Pip

January 21st, 2012, 5:28 pm #10

So quite bummed after getting a negative beta yesterday. Our doctor did not really have any answers as to why after we transferred 2 8 cell embryos that were "perfect" from a proven donor would not implant other than "it is always a 50/50 chance". He tried to be reassuring that we still had a great chance due to our 5 frozen embryos...still greater than 80% in getting a live birth is what he tried to tell me. So any advice from here on the next step on our way to the FET which he said we could do after one cycle? Should I have any other testing, immune etc? I think I will try acupuncture this time as well so when would I start that? My lining was at least 10 and I was pregnant naturally last year but miscarried at 7 weeks so I can get pregnant.
I am trying to be positive because I know I still have some good frozen ones and have several friends who have had successful frozen cycles. This is such a great resource and I have learned more here than from my physician, etc.....so thank you!
Sorry to hear your negative beta.Its so heartbreaking when we finally give up on OE and are told that this is our best chance.
I had 2 OE m/c last year and then BFN from 2 perfect 8 cell embies, great lining etc Again clinic had no feedback other than bad luck.I just could not understand how I could get pregnant twice last year with OE and not get pg with 20 something year old eggs.Our clinic has a 65% success rate so I guess we were the unlucky 35%. We have 2 frozen.
Because of my history I decided to get some immune testing done so we could rule everything out and not "waste" our remaining embies.
I'm still waiting for the results of NK panel but I have tested postive for anticardiolipin antibodies so I will prob need blood thinners for my FET.
I also tested postive for hidden C (clamydia)tested in menstrual blood, I couldnt believe it as all my swabs etc were negative.Apparently it can migrate higher up into the uterus and so is not picked up on swabs. Me and DH are now on megadose antibiotics.
Sorry I havent any advice for you but just wanted to let you know that I'm in the same boat as you.The very best of luck with your FET.
xx
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