Epilepsy in Rat Terriers

Danielle_Atencio
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Danielle_Atencio
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Joined: June 14th, 2009, 6:10 pm

April 7th, 2010, 8:14 pm #1

Meta posted this on one of the Rat Terrier boards, I thought that this may be of interest to some of the breeders on this board as well...

cross-post.

From Liz Hansen @ The University of Mo.

One thing that did catch my eye in the NRTA health survey was the report of over 1,000 dogs with epilepsy. Research to find the mutations responsible for many types of epilepsy in many different breeds has been a large focus of our efforts here for over 10 years. We have identified mutations for several syndromic epilepsies (diseases where seizures are one of several symptoms of the overall condition), and feel we are getting close to finding mutations for idiopathic epilepsy in several different breeds. We collaborate with researchers here in the US, and in Finland, England, and France as well. We would be very interested in samples & information from any epilepsy-affected Rat Terrier. Also very useful would be samples from the normal siblings, parents, and grandparents of these affected dogs. The forms and instructions for sending these samples can be found at our website online - go to www..CanineGeneticDiseases.net, click on EPILEPSY, and then go to SAMPLE SUBMISSION. If you have a way to make Rat Terrier fanciers aware of this research, and encourage them to participate, we would appreciate it very much - and it could lead to discovery of a mutation (or several mutations) responsible for the epilepsy seen in this breed, which would help to eliminate this troubling disease from the breed as well.

Liz
Liz Hansen
Animal Molecular Genetics Laboratory
University of Missouri - College of Veterinary Medicine
321 Connaway Hall
Columbia, MO 65211
Danielle Atencio
"Atencio Kennels"

http://www.imageevent.com/blazingsun
daniellekupfer1985@gmail.com
435-881-7435
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Wmratz
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Wmratz
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Joined: August 2nd, 2009, 5:49 am

April 12th, 2010, 4:37 pm #2

I had someone searching for puppies at one time last year who was very concerned about this health issue. Her previous dog died at age 7 due to complications from a seizure. She'd been having seizures of increasing magnitude since she was 1.5 yrs old. She bought the pup from a prominent breeder in the region, and kept in touch with owners of littermates as well. The issue arose in more than her own dog from that line so it's obvious that it's inherited, whatever "brand" of epiliepsy she had.

She didn't end up getting a pup from me this last time, but has kept in touch. (I just haven't had pups in over a year)
Carmeta French
Warren Mountain Rat Terriers
Vermont.
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Wildwood Deckers
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Wildwood Deckers
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Joined: May 19th, 2009, 11:42 am

April 12th, 2010, 7:58 pm #3

As far as I know its extremely hard to diagnose the reason of Epilepsy... it can be inherited, but it can also be caused by numerous other issues...

I'm epileptic, but never had a seizure untill I was in my mid 20s and havn't had one since with medication... and it doesn't run in my family.

Either way it is a misfire in the brain... when the brain misfires the outcome is a seizure...

Not all seizures are visible from an onlooker... anyone can see a grand mal, but visual seizures for the most part are only noticed by the one having the seizure, at times it can be somewhat seen by a dazed look... but it can happen at varying degrees...

Clyde
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Joined: July 14th, 2011, 4:18 pm

November 20th, 2011, 8:42 am #4

What will I do if my dog is having seizures? Any first aid for it?
A great rat terrier is produced by a responsible breeder and developed by dedicated owner.
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rbentrdr
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rbentrdr
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Joined: October 30th, 2014, 7:17 pm

October 30th, 2014, 7:39 pm #5

I see that this is an old post, but I wanted to add something. I have a Dalmatian who, at the day before he turned 21 months, had a seizure. I waited until he had another to put him on medication. Anyway, there is a holistic vet across town and I decided to go and see what she might have to say.
No "regular" yet had told me this: She said that half the dogs that have come to her with seizures, when put on a wheat free diet, quit having seizures. (She also said that we killed off most of the Irish Setters because when Russia quit buying our wheat, the dog food people snatched it up and put it in their recipe. Well, as many of you know, Irish Setters most times have celiac disease. That is when they have intractable diarrhea after ingesting wheat. )
Anyway, Raleigh is affected by too much wheat, but has seizures occasionally if I miss his medicine even without wheat in his diet. The day after he ate a LOAF OF BREAD he had a seizure. No, I don't usually feed him a loaf of bread. He got up on the kitchen counter like a cat! He is now, at nine, going through some type of neurological problem where he loses his balance, or just falls down standing in one spot. Fortunately, I had read about Coconut Oil and dementia, so I thought, "hmmm...maybe that would help." It did! I give it to him daily and it keeps the shakes and falling down at bay.
Well, the purpose of this long-winded first post is just to say - keep your dogs completely away from wheat if they have seizure disorder. AND away from corn, since it is all GM now and they have found many, many tumors in rats when they were fed corn.
Leslie
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jrod
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jrod
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Joined: July 13th, 2013, 1:16 am

November 1st, 2014, 7:50 pm #6

Thanks Leslie. I have a dog that has seizures and is on 150mg of Zonisamide twice a day. He has had seizures since he was about 6 weeks old and one of his litter mates had the same thing but didn't make it :(. The vet tested for all kinds of stuff, but couldn't find a cause. We,(my wife), spent over 2000 dollars trying to save all the pups. Out of six, three made it to adult hood but only one of the three survivors has seizures. They never mentioned wheat or anything. I will try to adjust their diet and see if anything changes.
Cheers
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