Opioid Abuse and ...

Joined: August 13th, 2005, 5:30 am

February 5th, 2018, 9:44 pm #1

<rant>

This piece in digboston just made me so angry.

https://digboston.com/dirty-old-boston-heroin-daze/

I've long been ranting about abuse - by corporations, manufacturers, doctors, pharmacists, and all the middle guys in between, from everything including opioids to medical devices (Medicare fraud abounds, and it is not the patients.  I wrote here some time ago documenting how many leg braces my mom was fitted for before I caught on to the gig - each different PT service contracted with one specific brace provider and insisted that she needed something different and she ended up with a closet full of useless braces, courtesy of Medicare.)

I am so tired of listening to people blame ____  (fill in the blank with your favorite choice) and are so willing (knowingly or not) to  just let the big guys skate.

The digboston piece looks at practices in the early 1900s.  Here ya go, today in West Virginia:

https://www.wvgazettemail.com/news/heal ... 6455b.html

</rant>
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Joined: April 27th, 2011, 4:12 pm

February 7th, 2018, 6:19 pm #2

Today the FDA declared the herbal supplement Kratom and Opioid. Pretty sure this is not a smart move.

https://www.nbcnews.com/storyline/ameri ... id-n845311
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Joined: November 13th, 2010, 12:37 pm

February 8th, 2018, 10:33 am #3

Im generally leery of "nutritional" supplements and the people who tout them, especially dangerous quacks like Dr. Oz. 

It would be easy to fall into the trap of dismissing the hype around kratom as the usual pseudoscientific woo that generally surrounds nutritional and alternative remedy fads. However, here is the view of a respected toxicologist on kratom and its new status:

Money quote toward the end:

I fear that by banning kratom, we are creating a significant issue by hindering research. I am a proponent of regulating kratom as limiting the excess, as controlling products that are entering the United States [to ensure] they show quality, that there is actually kratom inside when kratom is mentioned on the label. I support that health care providers should be serving as intermediaries to provide patients and consumers with advice on what they actually take.

But phasing it into Schedule 1 makes it very hard to further conduct research. And this is a new class of endo-alkaloids that act very distinctly different on opioid receptors. And just because the FDA hasn’t received an NDA [New Drug Application] or IND [Investigational New Drug application] to actually conduct a study with mitragynine to move it into a clinical trial, which we know costs . . . millions of dollars, doesn’t mean that it doesn’t have value for these 4 or 5 million kratom users, who I feel would have to go back to using prescription opioids or potentially going to street drugs.    
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