low or minis.

low or minis.

Beetle21
Beetle21

June 23rd, 2012, 5:09 am #1

Ive done 3 rounds of high stims IVF, resulting in a shut down, with 1 follicle always growing and . Where to now, low stims, or mini's

I come in and out of these boards, as I find I can get obsessive with making the wrong choices by comparing with what others are doing. Or come and go depending on my ups and downs.

turning 44 in 2 months - feeling defeated, but I just cant give up yet.
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Joined: December 20th, 2010, 7:38 pm

June 23rd, 2012, 5:16 am #2

I think it is more important to test water and try it out for one cycle to see if it works for you. Mini mainly uses Femara/Clomid + injectable boosters, and low-stim is mainly injectables + ganirelix/cetrotide. If you are on the east coast, go to SIRM-NY for EZ-IVF, and New Hope for mini. I believe that RMA also offers low stim and they have a good lab. Some people are great Clomid responders (like myself) but very mediocre injectables responders, and there are people who just cannot tolerate Clomid. You don't know which group you belong to until you try it out yourself.

If you are on the west coast, no choice, go straight to Life for mini, I am not sure if SIRM-LV offers EZ-IVF. If you are in the middle, well, I don't know.

All three of them have very solid labs.
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beetle21
beetle21

June 23rd, 2012, 5:23 am #3

I am on the west coast - I have been offered a consult with ccrm about lose dose, and cfp ( good stats for older gals) I cannot tolerate clomid at all. I wonder if I did to many high stim IVF's close together - I had good success on high stims last year - but zip this year.

I respond really well to estrogen priming, creating lots of follicles, but now I just need an excellent RE to gather up all the info and help me out!

Frightened as a birthday looms, I have the strength to do the long haul with minis as I already have a DD who is 2 and 2 months and I know the prize at the end.
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Joined: December 20th, 2010, 7:38 pm

June 23rd, 2012, 6:35 am #4

I don't know the price tag, but given their unparalleled lab, I think it is worth a try if you can afford it. CCRM has one of the most amazing IVM results in the country, I see lots of people having their eggs matured at the CCRM lab successfully. If you cannot tolerate Clomid, then CCRM's low stim with injectables is probably the best money can buy.

In my opinion, you really go to an IVF clinic for the lab, you can copy and paste different protocols, there is really no trade secret, having gone through 9 rounds of IVF, I know myself when to add dose, when to cruise, when to trigger. However, one thing I definitely cannot replicate is the lab's ability to culture my embryos.

To evaluate the lab, I look at their blast formation rate for my age group. If patients of my age group have embryos dying left and right before making it to the freezing grade, that is a bad sign.

Alternatively, ORM also has a very strong lab since the director Dr. Hesla was a former co-Director at CCRM (I know a couple of 42/43 who found success there after blast transfer), but when I asked a year ago, they told me they didn't offer low stim.

Same as you, I will do mini for as long as my wallet allows me to, and now it is just a part of my daily routine.
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